http://forum.lowyat.net/ Fri, 05 Jun 2026 10:02:27 +0800 FeedCreator 1.7.2 http://forum.lowyat.net/topic/5179721 <!--SPOILER BEGIN--><div class="spoilertop" onClick="openClose('c51dd576dba7caaaf65f9795dd401297')" style="font-weight: bold"><u>&raquo; Click to show Spoiler - click again to hide... &laquo;</u></div><div class="spoilermain" id="c51dd576dba7caaaf65f9795dd401297" style="display:none"><!--SPOILER END-->Ivermectin has proven in vitro activity against SARS-CoV-2 at a level 5 µM (micromole)<br />that is not possible to be achieved in vivo using current clinical recommended multiple<br />doses of 3, 6 and 12 mg tablets or a 6 mg/ml oral suspension per day (even at 1.7 mg/kg,<br />a 8.5 times the FDA-approved dosification, achieved plasma level was only 0.28 µM).<br /><br />Although high doses of ivermectin in adults or children are well tolerated (up to 1.7<br />mg/kg, 8.5 times the FDA-approved dosification), the clinical effects of effective doses<br />of ivermectin are unknown and may be associated with severe toxicity such as ataxia and<br />seizures.<br /><br />The results of clinical trials to date show imprecise and inconsistent effects of Ivermectin<br />in different studies suggesting irreproducibility of the results in different settings.<br />The data so far indicated that the clinical effects of ivermectin is likely due to chance<br />which means the reported effects observed were as good as rolling a dice; it has no real<br />or true effect on SARS-CoV-2 and COVID-19.<br /><br />The data situation is more of ‘no evidence of effect’ than ‘evidence of no effect’.<br />The public use of ivermectin is likely to continue while the scientific research continues to<br />accumulate its data.<br /><br />The speed of response from the scientific community in providing culturally effective<br />guidance to the public could be improved.<br /><br />The methodological issues of many clinical trials of Ivermectin on COVID-19 include<br />inadequate outcome rates for robust statistical analysis which increases the risk of<br />chance effect on the results, imbalance of the prognostic factors in the comparing<br />groups and unfair comparator to Ivermectin, co intervention and high risk of bias from<br />inadequate concealment of allocation during randomization process resulting in potential<br />selection bias, lack of blinding of participants and investigators resulting in potential<br />performance bias, lack of outcome assessors blinding resulting in potential detection<br />bias.<br /><br />The distribution of clinical effects of ivermectin could be the possible prevalence of bias<br />of the clinical research enterprise in the world.<!--SPOILER DIV--></div><!--SPOILER DIV--><br /><br /><a href='https://hpupm.upm.edu.my/upload/dokumen/20210730083320Newsletter_Ivermectin_on_COVID-19_Scientific_Plausibility,_Clinical_Evidence,_Clinical_Epidemiological_Issues_of_the_Studies_Full_Summary.pdf?fbclid=IwAR3r8fOdQoT45YxmjdJ1KQlqU6Yu6f_pf3NyIer2aIkL_8qQj-TiNKsAcPY' target='_blank'>SOURCE</a><br /><br /><b><u>TLDR: Ivermectin is sh&#33;t for covid-19</u></b> rainpearpirate Kopitiam Sun, 08 Aug 2021 09:25:38 +0800 http://forum.lowyat.net/topic/4952487 closed rainpearpirate Kopitiam Wed, 29 Apr 2020 22:53:38 +0800 http://forum.lowyat.net/topic/4854242 closed rainpearpirate Car Clubs Mon, 21 Oct 2019 11:17:53 +0800 http://forum.lowyat.net/topic/4845969 <b>Item(s):</b> Sony A6000 Body Only <br /><br /><b>Package includes:</b> camera body (black), box, strap, receipt, battery. <br /><br /><b>Price:</b> <b>RM1300</b><br /><br /><b>Warranty:</b> Nil. test kau kau during COD.<br /><br /><b>Dealing method:</b> COD only<br /> <br /><b>Location:</b> Bandar Puteri Puchong<br /><br /><b>Contact method/details:</b> PM<br />---<br /><br /><b>Item(s) conditions:</b> Mint 9.5/10. Shutter count 6807 <br /><br /><b>Reason for sale:</b> Not using rainpearpirate Digital SLRs &amp; Lenses Garage Sales Thu, 03 Oct 2019 09:49:35 +0800 http://forum.lowyat.net/topic/4809509 Hi i&#39;m looking for a phone to make calls &amp; whatsapp web only. So it will be plugged most of the time into the charger.<br /><br />Any recommendations for these phones preferably under RM300? New or used is okay.<br /><br />Thanks. rainpearpirate The Museum Of Kopitiam Thu, 18 Jul 2019 10:55:01 +0800 http://forum.lowyat.net/topic/4790458 Hi guys, I can&#39;t seem to decide to go for Maxis ONEBusiness Fiber, or just suck it up and pay for more UNIFI Biz Lite for my office.<br /><br />Location: Bandar Puteri Puchong.<br /><br />Usage: Just Three Desktops + CCTV/Alarm system. light upload/download usage. Mostly to retrieve small data from the cloud server. Very important to be running from 9am to 9pm.<br /><br />Thanks in advance&#33; rainpearpirate Maxis Fibre Sun, 09 Jun 2019 21:55:28 +0800